Medication Instructions For Skin Testing

Please follow these directions when getting ready for this test.  All antihistamines may affect the results of skin testing and therefore need to be stopped before the testing is done.  If the antihistamines are not stopped as recommended, testing may be delayed and another visit scheduled for the skin testing.


Please stop these antihistamines for 3 days before your appointment:


  • Actifed®, Dimetapp® (Brompheniramine)
  • Allegra®(Fexofenadine)
  • Astelin®, (Azelastine)
  • Astepro® (Azelastine)
  • Atarax®, Vistaril® (Hydroxyzine)
  • Benadryl® (Diphenhydramine)
  • Chlortrimeton® (Chlorpheniramine)
  • Claritin® (Loratadine)
  • Clarinex® (Desloratadine)
  • Patanase® (Olopatadine)
  • Phenergan® (Promethazine)
  • Rescon® (Chlorpheniramine/methscopolamine/phenylephrine)
  • Respa® (Guaifenesin/phenylephrine)
  • Rynatan® (Chlorpheniramine, Phenylephrine)
  • Tavist®, Antihist® (Clemastine)
  • XyZal® (Levocetirizine
  • Zyrtec® (Cetirizine)
  • Aller-Chlor®, Bromfed®, Drixoral®, Dura-tab®, Novafed-A®, Ornade®, Poly-Histine-D®, Trinalin® (Combination Medicines)


  • If you are taking an antihistamine that is not listed please stop the medicine for 3 days before your appointment. If you are not sure if the medicine you are taking is an antihistamine, ask your prescriber.
  • Do not take your asthma medications the morning of your appointment.
  • Sometimes antidepressants can also act as an antihistamine.  Let your doctor know if you are on any antidepressants before your skin testing.
  • If you are being seen for chronic hives, you do not need to stop taking antihistamines.


Continue to take all your other non-allergy medicine according to your regular, daily schedule.